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Flights from San Diego to St. Louis

Find cheap airlines flights from San Diego to St. Louis

Choose from 1 carriers that fly from San Diego to St. Louis, including American Airlines,,
American Airlines logo American Airlines

Cheap flight deals from San Diego to St. Louis

Find the cheapest flights from San Diego to St. Louis within the next three months. Book one-way flights from $120 or round-trip tickets from $520.

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  • One way

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Flight Info | San Diego to St. Louis

The distance between San Diego and St. Louis is about 2,514.9 km. It takes around 4 hours 7 minutes on average to fly from San Diego to St. Louis. The most popular month to St. Louis is March. The off-season for travel is March.

Cheapest one-way flight price $120
Cheapest round-trip ticket price $230
Off-season for travel March
Peak season for travel March
Flight distance 2,514.9 km
Average flight time 4 hours 7 minutes
Popular airline American Airlines

When is the cheapest time to fly from San Diego to St. Louis?

The best time to book the cheapest flights from San Diego to St. Louis is between Aug 3 and Aug 10. One-way ticket prices start at $119 according to our flight calendar.

Cheapest flights
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  • 20 27

  • Aug

    27 3
  • 3 10
  • 10 17
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  • 24 31

  • Sep

    31 7
  • 7 14
  • 14 21
  • 21 28
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from San Diego (SAN) to St. Louis (STL) the cheapest?

    Airlines adjust prices for flights from San Diego to St. Louis based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from San Diego (SAN) to St. Louis (STL) cost?

    According to Trip.com's data, the lowest price is around $400.

  • How long does it take to fly from San Diego (SAN) to St. Louis (STL) and what is the distance?

    It takes around 4 hours 7 minutes to fly from San Diego (SAN) to St. Louis (STL).

  • What are the most popular airlines that fly from San Diego (SAN) to St. Louis (STL)?

    Airlines with flights from San Diego (SAN) to St. Louis (STL): Southwest Airlines.

How to find a cheap flight from San Diego to St. Louis

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from San Diego to St. Louis. Book your flights at the right time and save more.
1
Be flexible with your travel dates to get the cheapest San Diego to St. Louis ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from San Diego to St. Louis for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is $120 for a one-way ticket on Tue, Aug 5.
2
Compare cheap San Diego to St. Louis flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from San Diego to St. Louis. The most affordable airline currently operating on this route is Frontier Airlines.
3
Set up a Price Alert to track fare drops.
Set up a Price Alert for your San Diego to St. Louis route to track ticket prices effortlessly—no need to check manually every day.
4
Don't miss out on cheap San Diego to St. Louis flight deals and promo codes.
Stay updated on the latest deals with Trip.com Deals and Promo Codes for cheap flights. Sign up for a free membership to unlock even more exclusive flight discounts.
5
Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
6
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from San Diego to St. Louis to access exclusive deals just for you.

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